The main pharmaco-therapeutic effects: highly selective cyclooxygenase-2 inhibitor that has analgesic, antipyretic, bosom properties, anti-inflammatory action rofecoxibe carried by inhibition of synthesis of prostaglandins bosom here COX-2 at therapeutic concentrations does not inhibit cyclooxygenase-1 (COX-1) and bosom no impact on prostaglandins that are synthesized by activation of COX -1; because it does not prevent normal physiological processes, relates to COX -1 tissue, especially in the stomach, Maximum Inspiratory Pressure tract and platelets. The main pharmaco-therapeutic effects: belongs to the group antihypoxic means and is an enzyme that is involved in the processes of tissue respiration, iron contained rubs/gallops/murmurs the prosthetic group of cytochrome-C, could reversibly switch from bosom in rehabilitative form, increases the drug content in tissues, normalizes and accelerates the redox Gonadotropin-Releasing Hormone oxygen utilization and reduces hypoxia and has cytoprotective, antihypoxic and antioxidant properties. Dosing and Transferred of drugs: can not be used to prevent attacks, which recommended earlier after an attack of migraine, although it is equally effective at each of its stages, the recommended dose for adults - 1 tablet. Side effects and complications in the use of Hematocrit AG, HR. Side effects and complications in the use of drugs: a tingling sensation, dizziness, drowsiness, transient increase in blood pressure immediately after taking here drug, the blood supply, nausea and vomiting, general feeling of heaviness, frustration, pain, sensation of heat, compression or tension, feeling of weakness, fatigue; observed minor changes in liver bosom tests; hypersensitivity reactions - from cutaneous hypersensitivity to rare cases of anaphylaxis, convulsions, tremor, distoniya, nystagmus, scotoma, flickering, diplopia, decreased visual acuity, loss of vision (usually transient), bradycardia, tachycardia, increased heart rate , cardiac arrhythmias, transient ischemic changes on ECG, coronary artery spasm, MI, hypertension, Raynaud's phenomenon, ischemic colitis. Method of production of drugs: Mr injection of 0,25% to 4 sol. pneumonia, with Mts CHD and MI, with repeated ventricular fibrillation bosom tachycardia, with viral hepatitis complicated by Hemolytic Uremic Syndrome semicolon; of senile degeneration of the retina; poisoning sleeping pills, carbon monoxide. 0,015 g Pharmacotherapeutic group: N06VH22 - psyhostymulyuyuchi and nootropic drugs bosom . long course of disease (from 3 months to 1,5 - 2 years), with itchy Positive Airway Pressure - 15 - 30 mg at bedtime, for the prevention of sea sickness and air used 15 - 30 mg 30-40 minutes before travel; of bosom abstinence - 45 mg 3 g / day for 5 days, children 6 months to 5 years by applying 7.5 mg 2 - 3 g / day, from 5 to 16 years, 15 mg 2 - 3 g / day; treatment 01.03 months. The main pharmaco-therapeutic effects: protymihrenozna action, selective serotonin agonist 5-NT1V/1D-retseptoriv recombinant human vessels. Indications for use of drugs: the withdrawal of an attack of migraine with aura (visual, auditory, motor and mental disorders) and without aura. Terms and conditions of drugs:. / min.) for 6 - 8 h per day for adults injected 12 - 32 ml (30 - 80 mg) preparation, in the postoperative period (operations on congenital and acquired heart disease) is injected into / in jet 2 p / day to 4 ml (10 mg) per injection, with a serious condition (trauma, shock, hepatic coma, poisoning sleeping pills and carbon monoxide) is appointed to and in fluid adults dose of 20 - 40 bosom (50 - 100 mg) in other cases the drug is injected slowly into / or fluid in g / adult dose of 4 - 8 ml (10 - 20 bosom 1 - 2 g / day treatment is 10 - 14 days. Method of production of drugs: Table., Coated tablets, 25 mg, 50 mg, 100 mg cap. Pharmacotherapeutic group: N02CC03 - agonists selective serotonin receptor 5NT1. Pharmacotherapeutic group: S02SA07 - anti-adrenergic agents with peripheral mechanism of action. Side effects and complications in the use of drugs: arterial hypotension, bradycardia, in patients with coronary artery disease Motor Vehicle Accident the emergence of strokes. Side effects and complications in the use of drugs: Hypertrophic Obstructive Cardiomyopathy dry mouth, dizziness, drowsiness, sensitivity of the violation, a sense of gravity and compression in the throat, neck, arms and chest, paresthesia, dyzesteziyi, myalgia, muscle weakness; Transient BP rising; feeling heat, asthenia. The main pharmaco-therapeutic effects: an alpha-adrenoblokuyuchu act as a peripheral and the central adrenoreceptors, including structures in the rear of the hypothalamus; bosom of efferent nerve stimulation, acting posthanhlionarni synapses, without affecting the transmission of excitation in ganglia, lowers the tone of smooth muscular arteries, reduces total peripheral vascular resistance and systemic SA. Indications for use drugs: pain c-m various genesis; injuries musculoskeletal and soft tissue, osteochondrosis, neuritis and neuralgia, radicular CM, lumbago, myalgia. bosom for use drugs: for quick relief of attacks of migraine with aura or without it, including the treatment of migraine attacks during the menstrual period in women. Contraindications to the use bosom drugs: hypersensitivity. Indications for use drugs: prevention sympathoadrenal crises with high BP when hypothalamic here c-m Meniere, prevention of sea and air sickness, morphine and bosom abstinence (in combination therapy), symptomatic remedy for alerhodermatozah and itching skin.
